These practical guidelines aim to improve the preparation of laboratory for practical examinations and candidates’ performance. They will enhance the teaching and learning process. They will also promote fair assessment since the candidates will be assessed on the same content taught. The National Examinations Council of Tanzania (NECTA) has prepared these guidelines to provide teachers with the necessary skills in preparing practical examinations. Agriculture subject teachers and laboratory technicians cannot prepare their practical examinations effectively if they are not familiar with the laboratory techniques that will lead to learning the required skills. The Agriculture subject teachers and laboratory technicians with the required skills will be able to prepare the laboratory for practical examinations effectively. This will improve the administration of examinations. These guidelines will also help teachers to efficiently and effectively teach their students laboratory practicals.